Xinxia Peng
Bio
I am a tenured Associate Professor of Infectious diseases in the Department of Molecular Biomedical Sciences, and a member of NC State Bioinformatics Research Center. I received my PhD in Computational Biology and Bioinformatics from the University of Tennessee – Oak Ridge National Laboratory Graduate School of Genome Science and Technology, under Computer Science Professor Dr. Michael Langston. I started as a Bioinformatics Manager at Seattle BioMed (now Center for Global Infectious Disease Research) after graduation. In 2008 I joined the University of Washington Department of Microbiology as a Computational Research Scientist, and was promoted to a Research Assistant Professor in 2012. I moved here at NC State in July 2016 as one of the Dean’s Faculty Excellence cluster hires, in the field of “Translational Genomics of Infectious Diseases,” and to be part of the Bioinformatics Research Center.
CERTIFICATIONS
Ph.D., Life Sciences: Computational Biology and Bioinformatics, University of Tennessee – Oak Ridge National Laboratory Graduate School of Genome Science and Technology, Oak Ridge, TN, 2005
M.S., Computer Science, University of Tennessee, Knoxville, TN, 2004
M.S., Foods and Nutrition, University of Georgia, Athens, GA, 2001
M.S., Biochemistry and Molecular Biology, East China Normal University, Shanghai, China, 1999
B.S., Biology, East China Normal University, Shanghai, China, 1996
Area(s) of Expertise
COMPUTATIONAL BIOLOGY AND BIOINFORMATICS, INFECTIOUS DISEASES
noncoding RNA, immunity, and target identification
Microbiome, immunity, and vaccine efficacy
Complex immune genes: genetic variation and transcriptional regulation
Genomics for infectious disease animal models: non-human primates and ferret
Publications
- Human long noncoding RNA,VILMIR,is induced by major respiratory viral infections and modulates the host interferon response , (2024)
- Pre-challenge gut microbial signature predicts RhCMV/SIV vaccine efficacy in rhesus macaques , (2024)
- Alternative splicing and genetic variation of mhc-e: implications for rhesus cytomegalovirus-based vaccines , COMMUNICATIONS BIOLOGY (2022)
- Coupling high-throughput mapping with proteomics analysis delineates cis-regulatory elements at high resolution , NUCLEIC ACIDS RESEARCH (2022)
- Phylogeny-guided microbiome OTU-specific association test (POST) , MICROBIOME (2022)
- Reduced Endometrial Ascension and Enhanced Reinfection Associated With Immunoglobulin G Antibodies to Specific Chlamydia trachomatis Proteins in Women at Risk for Chlamydia , JOURNAL OF INFECTIOUS DISEASES (2022)
- Single-Cell-Based High-Throughput Ig and TCR Repertoire Sequencing Analysis in Rhesus Macaques , JOURNAL OF IMMUNOLOGY (2022)
- Inferring environmental transmission using phylodynamics: a case-study using simulated evolution of an enteric pathogen , JOURNAL OF THE ROYAL SOCIETY INTERFACE (2021)
- Interleukin-15 response signature predicts RhCMV/SIV vaccine efficacy , PLOS PATHOGENS (2021)
- Sustained IL-15 response signature predicts RhCMV/SIV vaccine efficacy , (2021)